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EC 1.23.1.1 Details
EC number
1.23.1.1
Accepted name
(+)-pinoresinol reductase
Reaction
(+)-lariciresinol + NADP+ = (+)-pinoresinol + NADPH + H+
Other name(s)
pinoresinol/lariciresinol reductase,
pinoresinol-lariciresinol reductases,
(+)-pinoresinol/(+)-lariciresinol,
(+)-pinoresinol-(+)-lariciresinol reductase,
PLR
Systematic name
(+)-lariciresinol:NADP+ oxidoreductase
Comment
The reaction is catalysed in vivo in the opposite direction to that shown. A multifunctional enzyme that further reduces the product to the lignan (–)-secoisolariciresinol [EC 1.23.1.2, (+)-lariciresinol reductase]. Isolated from the plants Forsythia intermedia [1,2], Thuja plicata (western red cedar) [3], Linum perenne (perennial flax) [5] and Linum corymbulosum [6]. The 4-pro-R hydrogen of NADH is transferred to the 7-pro-R position of lariciresinol [1].
History
created 2013
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