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EC 2.3.3.19 Details
EC number
2.3.3.19
Accepted name
2-phosphonomethylmalate synthase
Reaction
acetyl-CoA + H2O + 3-phosphonopyruvate = (R)-2-(phosphonomethyl)malate + CoA
Other name(s)
2-phosphinomethylmalic acid synthase,
PMM synthase
Systematic name
acetyl-CoA:3-phosphonopyruvate C-acetyltransferase
Comment
The enzyme, isolated from several Streptomyces species, participate in the biosynthesis of certain phosphonate antibiotics. The enzyme is analogous to EC 2.3.3.1 (Si)-citrate synthase.
History
created 2017
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