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EC 2.3.3.10 Details
EC number
2.3.3.10
Accepted name
hydroxymethylglutaryl-CoA synthase
Reaction
acetyl-CoA + H2O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA
Other name(s)
(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating),
3-hydroxy-3-methylglutaryl CoA synthetase,
3-hydroxy-3-methylglutaryl coenzyme A synthase,
3-hydroxy-3-methylglutaryl coenzyme A synthetase,
3-hydroxy-3-methylglutaryl-CoA synthase,
3-hydroxy-3-methylglutaryl-coenzyme A synthase,
β-hydroxy-β-methylglutaryl-CoA synthase,
HMG-CoA synthase,
acetoacetyl coenzyme A transacetase,
hydroxymethylglutaryl coenzyme A synthase,
hydroxymethylglutaryl coenzyme A-condensing enzyme
Systematic name
acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
CAS registry number
9027-44-5
History
created 1961 as EC 4.1.3.5, transferred 2002 to EC 2.3.3.10
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