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2.3.1.256: N-terminal methionine Nalpha-acetyltransferase NatC

This is an abbreviated version!
For detailed information about N-terminal methionine Nalpha-acetyltransferase NatC, go to the full flat file.

Word Map on EC 2.3.1.256

Reaction

acetyl-CoA
+
an N-terminal-L-methionyl-L-isoleucyl-[protein]
=
an N-terminal-Nalpha-acetyl-L-methionyl-L-isoleucyl-[protein]
 +
CoA

Synonyms

EC 2.3.1.88, EGAP, embryonic growth-associated protein, hNaa30, MAK10, MAK3, MAK31, Mak31p, Mak3p, N-alpha acetyltransferase 30, N-alpha-acetyltransferase 30, N-terminal acetyltransferase, N-terminal acetyltransferase complex C, N-terminal acetyltransferase Naa30, NAA30, NAA35, NAA38, Nalpha-acetyltransferase, Nalpha-terminal acetyltransferase complex C, NAT12, NatC, PAM21, protein methionine N-acetyltransferase, RimI, RimI acetyltransferase, Rv3420c, TcNaa30, TcNaa35, TcNatC

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.256 N-terminal methionine Nalpha-acetyltransferase NatC

Natural Substrates Products

Natural Substrates Products on EC 2.3.1.256 - N-terminal methionine Nalpha-acetyltransferase NatC

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + an N-terminal-L-methionyl-L-histidyl-[protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-histidyl-[protein] + CoA
show the reaction diagram
-
-
-
?
acetyl-CoA + an N-terminal-L-methionyl-L-isoleucyl-[protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-isoleucyl-[protein] + CoA
show the reaction diagram
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[Arl8b protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[Arl8b protein] + CoA
show the reaction diagram
high activity, the full sequence is MLALISRRWGRPVGRRRRPVRVYP
-
-
?
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[L-A double-stranded RNA virus major coat protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[L-A double-stranded RNA virus major coat protein] + CoA
show the reaction diagram
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[mTOR protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[mTOR protein] + CoA
show the reaction diagram
highest activity. The full sequence is MLGTGPARWGRPVGRRRRPVRVYP
-
-
?
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[protein] + CoA
show the reaction diagram
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[RNP F protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[RNP F protein] + CoA
show the reaction diagram
the full sequence is MLGTEGGRWGRPVGRRRRPVRVYP
-
-
?
acetyl-CoA + an N-terminal-L-methionyl-L-leucyl-[RNP H protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-leucyl-[RNP H protein] + CoA
show the reaction diagram
high activity, the full sequence is MLGTEGGRWGRPVGRRRRPVRVYP
-
-
?
acetyl-CoA + an N-terminal-L-methionyl-L-lysyl-[protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-lysyl-[protein] + CoA
show the reaction diagram
-
-
-
?
acetyl-CoA + an N-terminal-L-methionyl-L-methionyl-[protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-methionyl-[protein] + CoA
show the reaction diagram
-
-
-
?
acetyl-CoA + an N-terminal-L-methionyl-L-phenylalanyl-[protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-phenylalanyl-[protein] + CoA
show the reaction diagram
acetyl-CoA + an N-terminal-L-methionyl-L-tryptophyl-[protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-tryptophyl-[protein] + CoA
show the reaction diagram
acetyl-CoA + an N-terminal-L-methionyl-L-tyrosinyl-[protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-tyrosinyl-[protein] + CoA
show the reaction diagram
acetyl-CoA + an N-terminal-L-methionyl-L-valyl-[protein]
an N-terminal-Nalpha-acetyl-L-methionyl-L-valyl-[protein] + CoA
show the reaction diagram
-
-
-
?
acetyl-CoA + N-terminal-L-methionyl-L-phenylalanyl-[Arl3 protein]
N-terminal-Nalpha-acetyl-L-methionyl-L-phenylalanyl-[Arl3 protein] + CoA
show the reaction diagram
-
-
-
?
additional information
?
-
almost no activity with nuclear factor kappaB p65 (MDELFPLRWGRPVGRRRRPVRVYP), kinesin KIF4A (MKEEVKGRWGRPVGRRRRPVRVYP), and high-mobility group protein A1 (SESSSKSRWGRPVGRRRRPVRVYP)
-
-
?