1.1.1.31: 3-hydroxyisobutyrate dehydrogenase
This is an abbreviated version!
For detailed information about 3-hydroxyisobutyrate dehydrogenase, go to the full flat file.
Reaction
+
=
+
+
Synonyms
3-HIBADH, 3-hydroxyisobutyrate dehydrogenase, 3-hydroxyisobutyrate dehydrogenase-I, 3-hydroxyisobutyric acid dehydrogenase, 3HIBDH-IV, 3HIBDHI, At4g20930, AtHDH1, beta-hydroxyisobutyrate dehydrogenase, HDH1, HIBADH, HIBDH
ECTree
KCat KM Value
KCat KM Value on EC 1.1.1.31 - 3-hydroxyisobutyrate dehydrogenase
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0.0448
(R)-3-hydroxyisobutyrate
at pH 8.5 and 30°C
1.773 - 604.1
(S)-3-hydroxyisobutyrate
4.99
3-hydroxy-2-methylpropanoate
25°C, pH 8.5
0.1036
3-hydroxypropanoic acid
at pH 8.5 and 30°C
0.0125
3-hydroxypropionate
-
pH 8.5, 37°C
10.23 - 15.4
3-hydroxypropionic acid
1.433 - 4.04
methyl (2S)-3-hydroxy-2-methylpropanoate
0.275 - 0.75
methyl DL-serine
0.498
NADP+
with (S)-3-hydroxyisobutyrate as cosubstrate, pH 8.5 and 30°C
1.773
(S)-3-hydroxyisobutyrate
at pH 8.5 and 30°C
4.993
(S)-3-hydroxyisobutyrate
at pH 8.5 and 25°C
37.1
(S)-3-hydroxyisobutyrate
-
at pH 10.0, temperature not specified in the publication
464.9
(S)-3-hydroxyisobutyrate
-
at 30°C and pH 9.0
604.1
(S)-3-hydroxyisobutyrate
-
at 37°C and pH 9.0
10.23
3-hydroxypropionic acid
-
at 30°C and pH 9.0
15.4
3-hydroxypropionic acid
-
at 37°C and pH 9.0
0.044
L-serine
at pH 8.5 and 30°C
0.404
L-serine
-
at 30°C and pH 9.0
1.46
L-serine
-
at 37°C and pH 9.0
1.433
methyl (2S)-3-hydroxy-2-methylpropanoate
-
at 30°C and pH 9.0
4.04
methyl (2S)-3-hydroxy-2-methylpropanoate
-
at 37°C and pH 9.0
0.275
methyl DL-serine
-
at 30°C and pH 9.0
0.75
methyl DL-serine
-
at 37°C and pH 9.0
2.1
NAD+
with (S)-3-hydroxyisobutyrate as cosubstrate, pH 8.5 and 30°C
7.571
NAD+
at pH 8.5 and 25°C
42.44
NAD+
-
with 3-hydroxypropionic acid as cosubstrate, at 30°C and pH 9.0
55.1
NAD+
-
at pH 10.0, temperature not specified in the publication