EC Number |
Protein Variants |
Reference |
---|
2.4.1.1 | D238A |
15fold decrease in Vmax, 10fold decrease in Km for glucose 1-phosphate, 10fold increase in Ka for AMP, 10-20fold increase in Ki for glucose |
488293 |
2.4.1.1 | D238N |
15fold decrease in Vmax, 10fold decrease in Km for glucose 1-phosphate, 10fold increase in Ka for AMP, 10-20fold increase in Ki for glucose |
488293 |
2.4.1.1 | D339A |
significantly reduced activity |
488299 |
2.4.1.1 | E382A |
significantly reduced activity |
488299 |
2.4.1.1 | E88A |
significantly reduced activity |
488299 |
2.4.1.1 | F285L |
2fold decrease in Vmax, 10fold decrease in affinity for caffeine, 3fold increase in Ka for AMP |
488293 |
2.4.1.1 | F39L |
mutant with enhanced thermostability and resistance to proteolytic degradation |
671424 |
2.4.1.1 | F39L/N135S |
mutant with enhanced thermostability and resistance to proteolytic degradation |
671424 |
2.4.1.1 | F39L/N135S/T706I |
mutant with enhanced thermostability and resistance to proteolytic degradation |
671424 |
2.4.1.1 | F39L/T706I |
mutant with enhanced thermostability and resistance to proteolytic degradation |
671424 |