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EC Number	Protein Variants	Commentary	Reference
1.6.3.5	more	mutation of Ren1 to address poor solubility, low expression levels, misfolding, aggregation, and other stability factors. m5Ren1 introduces 19 mutations and m6Ren1 introduces 27 mutations to the primary sequence of renalase. Both m5Ren1 and m6Ren1 include one replacement for a cysteine residue to the wild-type sequence	765659

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Release 2023.1 (January 2023)