Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Protein Variants

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 131 > >>
download as CSV
download all results as CSV
EC Number Protein Variants Commentary Reference
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40A339E the mutant of isoform nonC4-NADP-ME shows increased catalytic efficiency compared to the wild type enzyme 762000
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40A387G site directed mutagenesis, mutation at the NADP+ binding site, mutant shows 48fold decreased kcat and 4.3 and 5.8fold increased Km for NADP+ and L-malate, respectively, compared to the wild-type enzyme, no activity with NAD+ 656120
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40A392G site directed mutagenesis, mutation at the NADP+ binding site, mutant shows unaltered kcat, but 3.5 and 2.6fold increased Km for NADP+ and L-malate, respectively, and increased activity with NAD+ compared to the wild-type enzyme 656120
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40C192A marked decrease in kcat value, less than 10% of wild-type, with concomitant increase in Km value for NADP+. Unlike wild-type, activity is not significantly changed in presence of oxidant iodosobenzoate 723390
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40C192A site-directed mutagenesis of isozyme ZmC4-NADP-ME, the mutation does not affect the tetrameric state, the mutant displays lower malate affinity than the wild-type enzyme 723390
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40C231A marked decrease in kcat value, less than 10% of wild-type, with concomitant increase in Km value for NADP+. Similar to wild-type, activity decreases in presence of oxidant iodosobenzoate 723390
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40C231A site-directed mutagenesis of isozyme ZmC4-NADP-ME, the mutation does not affect the tetrameric state, the mutant displays lower malate affinity than the wild-type enzyme 723390
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40C246A marked decrease in kcat value, less than 10% of wild-type, with concomitant increase in Km value for NADP+. Unlike wild-type, activity is not significantly changed in presence of oxidant iodosobenzoate 723390
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40C246A site-directed mutagenesis of isozyme ZmC4-NADP-ME, the mutation does not affect the tetrameric state, C246A exhibits a nearly 5fold increase in its affinity towards NADP+ and a 3fold decrease for malate compared to the wild-tpe enzyme 723390
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40C270A marked decrease in kcat value, less than 10% of wild-type, with concomitant increase in Km value for NADP+. Unlike wild-type, activity is not significantly changed in presence of oxidant iodosobenzoate 723390
Results 1 - 10 of 131 > >>
download as CSV
download all results as CSV