EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category  |
Confidence Level |
|---|
   3.4.22.52 | Alzheimer Disease |
25641096 |
Truncation and activation of GSK-3? by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease. |
causal interaction
unassigned |
3
0 |
| 3.4.22.52 | Alzheimer Disease |
25918155 |
Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE. |
causal interaction
unassigned |
1
0 |
| 3.4.22.52 | Ataxia |
28321562 |
CAPN1 mutations are associated with a syndrome of combined spasticity and ataxia. |
causal interaction
unassigned |
4
0 |
| 3.4.22.52 | Ataxia |
30572172 |
CAPN1 mutations: Expanding the CAPN1-related phenotype: From hereditary spastic paraparesis to spastic ataxia. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
4
3
1
0 |
| 3.4.22.52 | Ataxia |
32860341 |
Novel CAPN1 mutations extend the phenotypic heterogeneity in combined spastic paraplegia and ataxia. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 3.4.22.52 | Atrial Fibrillation |
18001554 |
[Effect of calpain 1 on structural remodeling and contractile dysfunction in atrial fibrillation: experiment with dogs] |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
1
3
3
1 |
| 3.4.22.52 | Brain Diseases |
32328086 |
Deletion of the Capn1 Gene Results in Alterations in Signaling Pathways Related to Alzheimer's Disease, Protein Quality Control and Synaptic Plasticity in Mouse Brain. |
causal interaction
diagnostic usage
unassigned |
4
1
0 |
| 3.4.22.52 | Brain Injuries, Traumatic |
8858942 |
mu-calpain activation and calpain-mediated cytoskeletal proteolysis following traumatic brain injury. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 3.4.22.52 | Brain Injuries, Traumatic |
9469158 |
Subcellular localization and duration of mu-calpain and m-calpain activity after traumatic brain injury in the rat: a casein zymography study. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
4
1 |
| 3.4.22.52 | Brain Injuries, Traumatic |
22367208 |
Targeted gene inactivation of calpain-1 suppresses cortical degeneration due to traumatic brain injury and neuronal apoptosis induced by oxidative stress. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
4 |
