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EC Number Crystallization (Commentary)
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.189crystal structures of apo-form RlmCD and its complex with SAH. A long linker in the central domain of RlmCD is the key factor in determining its substrate selectivity
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.189structure of RlmCD in complex with its cofactor and the RNA substrate containing U747 at 2.00 A or U1939 at 3.10 A. The side-chain rearrangement of F145 displays an unusual mechanism through which RlmCD can discriminate between U747- and U1939-containing RNA substrate by switching the intermolecular aromatic stacking between protein and RNA on/off
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