1.4.3.1 | structure of mutants C141Y and C143G, to 3.22 A resolution. The FAD-binding domain is comprised of residues 1-46, 143-192, 282-335 with the canonical dinucleotide binding fold observed in several flavoenzymes, and the substrate-binding domain (residues 47-142, 193-281) is characterized by a large, eight-stranded, mixed beta-sheet |