EC Number   |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Reference |
|---|
   3.4.22.15 | -999 |
- |
- |
647919, 647927, 647931, 647940 |
| 3.4.22.15 | -999 |
- |
high glucose concentration dose-dependently reduces cathepsin L activity (up to approx. 65% of initial activity), dose range tested 5.5 mM to 30 mM, substrat N-benzyloxycarbonyl-Phe-Arg-4-methoxy-beta-naphthylamide, fluorogenic assay |
699608 |
| 3.4.22.15 | -999 |
- |
high glucose concentrations dose-dependently reduce matrix degrading activity of endothelial progenitor cells, dose range tested 5.5 mM to 30 mM |
699608 |
| 3.4.22.15 | -999 |
- |
reduced cathepsin L activity in patients with diabetes |
699608 |
| 3.4.22.15 | -999 |
- |
the crude extract has a specific activity of 110 units/mg protein, the 15fold purified enzyme has a specific activity of 1644 units/mg protein at pH 4.5 and 55°C, one enzyme unit is defined as the absorbance at 380 nm given by 0.001 mM of free 7-amino-4-methylcoumarin per min |
712052 |
| 3.4.22.15 | 0.008 |
- |
tert-butoxycarbonyl-Val-Pro-Arg-methylcoumarin 7-amide, 0484 nM enzyme, 50 mM sodium acetate, 1 mM dithiothreitol, pH 5.0, 24°C |
667321 |
| 3.4.22.15 | 0.01 |
- |
tert-butoxycarbonyl-Arg-Val-Arg-Arg-methylcoumarin 7-amide, 0484 nM enzyme, 50 mM sodium acetate, 1 mM dithiothreitol, pH 5.0, 24°C |
667321 |
| 3.4.22.15 | 0.012 |
- |
succinyl-Leu-Leu-Val-Tyr-methylcoumarin 7-amide, 0484 nM enzyme, 50 mM sodium acetate, 1 mM dithiothreitol, pH 5.0, 24°C |
667321 |
| 3.4.22.15 | 0.03 |
- |
tert-butoxycarbonyl-Arg-Arg-methylcoumarin 7-amide, 0484 nM enzyme, 50 mM sodium acetate, 1 mM dithiothreitol, pH 5.0, 24°C |
667321 |
| 3.4.22.15 | 0.0517 |
- |
- |
647930 |
