EC Number |
General Information |
Reference |
---|
2.1.1.373 | evolution |
evolutionary analysis suggests that eukaryotic enzyme (DSYB) originates in bacteria and is passed to eukaryotes early in their evolution |
-, 759840 |
2.1.1.373 | evolution |
the bacterial DsyB enzyme is homologous to the algal DSYB enzyme and likely originates in bacteria |
759736 |
2.1.1.373 | malfunction |
metagenome data show that bacterial dsyB mutants are less tolerant of deep ocean pressures than wild-type strains |
759828 |
2.1.1.373 | metabolism |
the enzyme catalyses the key step of dimethylsulfoniopropionate biosynthesis in phytoplankton |
-, 759840 |
2.1.1.373 | metabolism |
the enzyme catalyses the key step of dimethylsulfoniopropionate biosynthesis. Dimethylsulfoniopropionate plays a pivotal role in the marine sulfur cycle |
-, 758701 |
2.1.1.373 | physiological function |
enzyme is involved in synthesis of dimethylsulfoniopropionate. A DsyB disruption mutant no longer produces dimethylsulfoniopropionate but accumulates approximately threefold more 4-methylthio-2-hydroxybutyrate than the wild-type |
-, 763510 |
2.1.1.373 | physiological function |
recombinant expression in Rhizobium leguminosarum confers dimethylsulfoniopropionate production from 4-methylthio-2-hydroxybutanoate |
-, 763510 |
2.1.1.373 | physiological function |
the enzyme is involved in biosynthesis of dimethylsulfoniopropionate from methionine. Sulfur deficiency increases the activity of the sulfur assimilation enzyme O-acetyl serine sulfhydrylase but decreases the 2-hydroxy-4-(methylsulfanyl)butanoate S-methyltransferase activity |
759654 |
2.1.1.373 | physiological function |
the enzyme is involved in biosynthesis of the marine osmolyte dimethylsulfoniopropionate (DMSP). The physiological function for DMSP in hydrostatic pressure protection. Bacteria are key DMSP producers in deep seawater and sediment. The genetic potential for bacterial DMSP synthesis via the dsyB gene and its transcription is greater in the deep ocean, and is highest in the sediment.s DMSP catabolic potential is present throughout the trench waters, but is less prominent below 8000 m, perhaps indicating a preference to store DMSP in the deep for stress protection. Deep ocean bacterial isolates show enhanced DMSP production under increased hydrostatic pressure. No eukaryotic DMSP synthesis genes are detected in any metagenomes, even from the surface waters |
759828 |
2.1.1.373 | physiological function |
the enzyme is involved in the 3-dimethylsulfoniopropionate synthesis pathway. The enzyme may be involved to confer osmotolerance. The product (2R)-4-(dimethylsulfaniumyl)-2-hydroxybutanoate is an osmoprotectant |
759975 |