EC Number   |
Expression |
Reference |
|---|
    2.4.2.4 | down |
the enzyme expression is is inversely correlated with estradiol concentrations in the endometrium |
705495 |
| 2.4.2.4 | down |
treatment with 0.005-0.04 mM tamoxifen decreases mRNA and protein levels through AKT inactivation |
735645 |
| 2.4.2.4 | more |
capecitabine does not affect enzyme activity and expression |
701722 |
| 2.4.2.4 | up |
chorionic gonadotropin36 and a combination of progesterone and transforming growth factor b1 upregulate the enzyme expression. The enzyme is also upregulated in several diseases, detailed overview |
705495 |
| 2.4.2.4 | up |
EGF receptor inhibition may lead to TP overexpression, and tissue hypoxia secondary to low hemoglobin levels may induce TP overexpression |
759291 |
| 2.4.2.4 | up |
the enzyme is highly upregulated in a variety of solid tumours |
759143 |
| 2.4.2.4 | up |
the enzyme is strongly induced in the serum-deprived nasopharyngeal carcinoma cell lines TW-01, TW-02, and TW-04, the serum deprivation-triggered upregulation of the enzyme is due to mRNA stabilization, not protein stabilization or transcriptional activation requiring the mRNA CU-rich element sequence and heterogeneous nuclear ribonucleoprotein K, mechanism and kinetics, overview |
706011 |
