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EC Number
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1.8.1.4
down
the expression level of the enzyme is significantly lower in the head and neck cancer than in normal cells
765743
1.8.1.4
down
the full-length isoform of dihydrolipoamide dehydrogenase is induced by Nutin-3, while the shorter isoform of dihydrolipoamide dehydrogenase is downregulated by Nutlin-3, immunochemical analysis of dihydrolipoamide dehydrogenase protein levels after MDM2 perturbation, verview
743767
1.8.1.4
up
the full-length isoform of dihydrolipoamide dehydrogenase is induced by Nutin-3, while the shorter isoform of dihydrolipoamide dehydrogenase is downregulated by Nutlin-3, immunochemical analysis of dihydrolipoamide dehydrogenase protein levels after MDM2 perturbation, overview. Depletion of MDM2 using siRNA elevates dihydrolipoamide dehydrogenase in Nutlin-3-treated cells. An increase in MDM2/dihydrolipoamide dehydrogenase complexes in the nucleus is further enhanced by the nuclear export inhibitor Leptomycin B
743767
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