EC Number   |
Expression |
Reference |
|---|
   1.13.11.63 | down |
addition of beta-carotene to the diet reduces the mRNA levels of BCMO1 in the liver in both genotypes, haplotypes AN57A and GN57G |
744613 |
| 1.13.11.63 | down |
endogenous nuclear HNF-1alpha and HNF-4alpha proteins competitively bind these sites in Caco-2 BBe cells. BCMO1 gene expression levels and promoter activity are significantly decreased in HNF-1alpha siRNA-transfected Caco-2 BBe cells. In contrast, HNF-4alpha siRNA-transfected cells exhibit a significant increase in BCMO1 gene expression and promoter activity. Mutation of these overlapping binding sites dramatically decreases BCMO1 promoter activity |
745662 |
| 1.13.11.63 | down |
expression of enzyme BCMO1 is lower in liver and intestine from dehydroepiandrosterone fed rats but higher in testis and unaffected in lung and kidney compared to controls |
-, 745597 |
| 1.13.11.63 | more |
mRNA is abundant at embryonic day 7, with lower expression at embryonic days 11, 13, and 15 |
438231 |
| 1.13.11.63 | up |
endogenous nuclear HNF-1alpha and HNF-4alpha proteins competitively bind these sites in Caco-2 BBe cells. BCMO1 gene expression levels and promoter activity are significantly decreased in HNF-1alpha siRNA-transfected Caco-2 BBe cells. In contrast, HNF-4alpha siRNA-transfected cells exhibit a significant increase in BCMO1 gene expression and promoter activity. Mutation of these overlapping binding sites dramatically decreases BCMO1 promoter activity |
745662 |
| 1.13.11.63 | up |
expression of enzyme BCMO1 is lower in liver and intestine from dehydroepiandrosterone fed rats but higher in testis and unaffected in lung and kidney compared to controls |
-, 745597 |
| 1.13.11.63 | up |
nitrofen increases maternal but not fetal Bcmo1,2 expression in the placenta in nitrofen-induced congenital diaphragmatic hernia, CDH, group. The markedly increased decidual Bcmo1,2 expression suggests that nitrofen may trigger local, decidual retinol synthesis in the nitrofen model of CDH |
-, 745967 |
| 1.13.11.63 | up |
the enzyme expression is induced by Zn2+ |
763953 |
