EC Number   |
Expression |
Reference |
|---|
    1.1.1.21 | down |
fidarestat significantly inhibits the enzyme activity as well as the enzyme expression |
738282 |
| 1.1.1.21 | down |
inhibition of the enzyme activity also inhibits the expression of the enzyme protein in xenograft tissue |
713006 |
| 1.1.1.21 | up |
aldose reductase is upregulated in hyperglycemia |
738031 |
| 1.1.1.21 | up |
expression of enzyme aldose reductase is upregulated in microglia/macrophages after spinal cord injury in wild-type mice. In enzyme knockout mice, spinal cord injury leads to smaller injury lesion areas compared to wild-type |
-, 739113 |
| 1.1.1.21 | up |
lippolysaccharide, from Salmonella enterica serotype typhimurium, induces the enzyme in mouse retina |
-, 737617 |
| 1.1.1.21 | up |
maximum activity is recorded with 3.25% xylose, 0.125% MgSO4 using 24 h old inoculum after 108 h of incubation at 32.5 °C. The enzyme activity shows 3.81folds increase over the control (33.07 U/mg) with up to 64% xylose conversion after optimization |
763768 |
| 1.1.1.21 | up |
upregulation of the aldose reductase pathway with aging |
710793 |
