EC Number   |
Expression |
Reference |
|---|
    1.1.1.188 | down |
AKR1B1 shows decreased expression in neoplastic disease, AKR1B1 activity might be suppressed in tumor cells in breast cancer tissues |
740999 |
| 1.1.1.188 | more |
PGF2S is constitutively expressed throughout promastigote development |
-, 762092 |
| 1.1.1.188 | more |
treatment with estradiol and/or progesterone affects neither PGF2alpha secretion nor enzyme PGFS expression at any phase after 12 h of culture, while related enzymes PG-endoperoxide synthase (PTGS2) and PGE2 synthase (PGES) are both upregulated by estradiol and progesterone during pseudopregnancy |
726469 |
| 1.1.1.188 | up |
after treatment with estradiol, PGFS mRNA expression increases 2.9fold after 4 h and reaches a maximum level of 3.8-4.4fold after 8 to 24 h |
762365 |
| 1.1.1.188 | up |
AKR1B1 expression is induced by interleukin-1beta leading to a higher production of prostaglandin F2alpha |
741357 |
| 1.1.1.188 | up |
AKR1B3 mRNA is expressed in preadipocytes, and its level increases about 4fold at day 1 after initiation of adipocyte differentiation, and then quickly decreases the following day to a level lower than that in the preadipocytes |
712494 |
| 1.1.1.188 | up |
AKR1C3 expression is induced by interleukin-1beta leading to a higher production of prostaglandin F2alpha |
741357 |
| 1.1.1.188 | up |
AKR1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism. It is upregulated by its substrate, prostaglandin D2 |
740413 |
| 1.1.1.188 | up |
expression is significantly up-regulated by oestradiol plus progesterone at oestrus and the mid phase of pseudopregnancy and is also up-regulated by a single treatment with progesterone at late pseudopregnancy. Simultaneous incubation with oestradiol and progesterone up-regulates prostaglandin-endoperoxide synthase PTGS2 gene expression at oestrus and mid-luteal phase. Treatment with oestradiol and /or progesterone affects neither prostaglandin F2alpha secretion nor prostaglandin F2alpha synthase expression at any phase after 12 h of culture |
726469 |
| 1.1.1.188 | up |
expression of AKR1B1 is upregulated in the fetal membranes in association with term labor, during labor tumor necrosis factor TNF upregulates the AKR1B1 protein expression |
740487 |
