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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
3.4.22.B80
763894
A dual-color fluorescent probe allows simultaneous imaging of main and papain-like proteases of SARS-CoV-2-infected cells for accurate detection and rapid inhibitor screening
Angew. Chem. Int. Ed. Engl.
61
e202113617
2022
Severe acute respiratory syndrome coronavirus 2
-
3.4.22.B80
762892
A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease
Cell Rep.
36
109754
2021
Severe acute respiratory syndrome coronavirus 2
34547223
3.4.22.B80
765673
A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
Proc. Natl. Acad. Sci. USA
105
16119-16124
2008
severe acute respiratory syndrome coronavirus
18852458
3.4.22.B80
765795
Aloin isoforms (A and B) selectively inhibits proteolytic and deubiquitinating activity of papain like protease (PLpro) of SARS-CoV-2 in vitro
Sci. Rep.
12
2145
2022
Severe acute respiratory syndrome coronavirus 2
35140265
3.4.22.B80
763479
An in silico molecular dynamics simulation study on the inhibitors of SARS-CoV-2 proteases (3CLpro and PLpro) to combat COVID-19
Mol. Simul.
47
1168-1184
2021
Severe acute respiratory syndrome coronavirus 2
-
3.4.22.B80
755740
Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
Acta Pharm. Sin. B
10
766-788
2020
Severe acute respiratory syndrome coronavirus 2
32292689
3.4.22.B80
762789
Binding of SARS-CoV covalent non-covalent inhibitors to the SARS-CoV-2 papain-like protease and ovarian tumor domain deubiquitinases
Biomolecules
11
802
2021
Severe acute respiratory syndrome coronavirus 2
34071582
3.4.22.B80
757319
Chalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS-CoV
J. Enzyme Inhib. Med. Chem.
31
23-30
2016
Severe acute respiratory syndrome-related coronavirus
25683083
3.4.22.B80
755700
Characterization and noncovalent inhibition of the deubiquitinase and deISGylase activity of SARS-CoV-2 papain-like protease
ACS Infect. Dis.
6
2099-2109
2020
Severe acute respiratory syndrome coronavirus 2
32428392
3.4.22.B80
757248
Chemical-informatics approach to COVID-19 drug discovery Monte Carlo based QSAR, virtual screening and molecular docking study of some in-house molecules as papain-like protease (PLpro) inhibitors
J. Biomol. Struct. Dyn.
2020
1-10
2020
Severe acute respiratory syndrome coronavirus 2
32568618
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