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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
3.4.22.69
763894
A dual-color fluorescent probe allows simultaneous imaging of main and papain-like proteases of SARS-CoV-2-infected cells for accurate detection and rapid inhibitor screening
Angew. Chem. Int. Ed. Engl.
61
e202113617
2022
Severe acute respiratory syndrome coronavirus 2
-
3.4.22.69
754405
A guideline for homology modeling of the proteins from newly discovered betacoronavirus, 2019 novel coronavirus (2019-nCoV)
J. Med. Virol.
92
1542-1548
2020
Severe acute respiratory syndrome coronavirus 2
32181901
3.4.22.69
765795
Aloin isoforms (A and B) selectively inhibits proteolytic and deubiquitinating activity of papain like protease (PLpro) of SARS-CoV-2 in vitro
Sci. Rep.
12
2145
2022
Severe acute respiratory syndrome coronavirus 2
35140265
3.4.22.69
765841
Assessment of activity of chalcone compounds as inhibitors of 3-chymotrypsin like protease (3CLPro) of SARS-CoV-2 in silico study
Struct. Chem.
2022
1-17
2022
Severe acute respiratory syndrome coronavirus 2
35153452
3.4.22.69
755639
Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor
Vet. Microbiol.
237
108398
2019
feline coronavirus
31585653
3.4.22.69
755419
Conformational flexibility of a short loop near the active site of the SARS-3CLpro is essential to maintain catalytic activity
Sci. Rep.
6
20918
2016
Severe acute respiratory syndrome-related coronavirus
26879383
3.4.22.69
755546
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved alpha-ketoamide inhibitors
Science
368
409-412
2020
Severe acute respiratory syndrome coronavirus 2
32198291
3.4.22.69
755546
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved alpha-ketoamide inhibitors
Science
368
409-412
2020
Severe acute respiratory syndrome-related coronavirus
32198291
3.4.22.69
764532
Design and various in silico studies of the novel curcumin derivatives as potential candidates against COVID-19-associated main enzymes
Comput. Biol. Chem.
98
107657
2022
Severe acute respiratory syndrome coronavirus 2
35259661
3.4.22.69
764802
Design of SARS-CoV-2 Mpro, PLpro dual-target inhibitors based on deep reinforcement learning and virtual screening
Future Med. Chem.
14
393-405
2022
Severe acute respiratory syndrome coronavirus 2
35220726
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