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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
3.4.22.B50
670702
Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme
Proc. Natl. Acad. Sci. USA
103
5717-5722
2006
Alphacoronavirus SARS-CoV
16581910
3.4.22.B50
681685
Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication
J. Virol.
81
3922-3932
2007
Human coronavirus 229E
17251282
3.4.22.B50
681691
Proteolytic processing and deubiquitinating activity of papain-like proteases of human coronavirus NL63
J. Virol.
81
6007-6018
2007
Human coronavirus NL63
17392370
3.4.22.B50
718347
Deubiquitinase activity and regulation of antiviral innate immune responses by papain-like proteases of human coronavirus NL63
Prog. Biochem. Biophys.
37
871-880
2010
Human coronavirus NL63
-
3.4.22.B50
718000
Comparison of SARS and NL63 papain-like protease binding sites and binding site dynamics: inhibitor design implications
J. Mol. Biol.
414
272-288
2011
Human coronavirus NL63
22004941
3.4.22.B50
718275
PLP2 of mouse hepatitis virus A59 (MHV-A59) targets TBK1 to negatively regulate cellular type I interferon signaling pathway
PLoS ONE
6
e17192
2011
Murine hepatitis virus
21364999
3.4.22.B50
732827
Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells
Proc. Natl. Acad. Sci. USA
110
E838-E847
2013
equine arteritis virus
23401522
3.4.22.B50
732725
Enhancement of proteolytic activity of a thermostable papain-like protease by structure-based rational design
PLoS ONE
8
e62619
2013
Tabernaemontana divaricata
23671614
3.4.22.B50
732257
The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase
J. Gen. Virol.
94
1554-1567
2013
porcine epidemic diarrhea virus
23596270
3.4.22.B50
731069
Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease
Acta Crystallogr. Sect. D
70
572-581
2014
Severe acute respiratory syndrome-related coronavirus
24531491
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