EC Number   |
Application |
Reference |
|---|
    1.1.1.35 | biofuel production |
3-hydroxybutyryl-CoA dehydrogenase is an enzyme involved in the synthesis of the biofuel n-butanol by converting acetoacetyl-CoA to 3-hydroxybutyryl-CoA, molecular mechanism of n-butanol biosynthesis, overview |
-, 739989 |
| 1.1.1.35 | biofuel production |
the highly efficient mutant enzyme K50A/K54A/L232Y can be useful for increasing the production rate of n-butanol in biofuel production |
740854 |
| 1.1.1.35 | diagnostics |
the enzyme can be used as marker for early immunonological detection of infection by Leptospira in urine and of leptospirosis, a global zoonosis caused by pathogenic Leptospira |
-, 740235 |
| 1.1.1.35 | medicine |
HADH protects against excess amino acid-induced insulin secretion |
699171 |
| 1.1.1.35 | medicine |
lack of Hadh2 activity may impart early developmental problems, leading to embryo lethality. In addition to the 3-hydroxyacyl-CoA dehydrogenase activity, the HSD10 (formerly Hadh2) activity is also relevant to the metabolism and meiotic maturation of oocytes |
695470 |
| 1.1.1.35 | medicine |
the leptospiral enzyme is an early urinary biomarker of leptospirosis |
-, 761222 |
| 1.1.1.35 | pharmacology |
the short-chain 3-hydroxyacyl-CoA dehydrogenase is a target for intervention in case of Alzheimer's disease and Parkinson's disease |
673530 |
| 1.1.1.35 | synthesis |
the enzyme is used in the biosynthesis of n-butanol from acetyl-CoA by the reduction of acetoacetyl-CoA to (S)-3-hydroxybutyryl-CoA |
-, 739815 |
| 1.1.1.35 | synthesis |
the highly efficient mutant enzyme K50A/K54A/L232Y can be useful for increasing the production rate of n-butanol |
740854 |
