Cloned (Comment) | Organism |
---|---|
- |
Sulfurisphaera tokodaii |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the Holliday junction-specific endonuclease from Sulfolobus tokodaii (StoHjc) inhibits in vitro | Sulfurisphaera tokodaii |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | Mg2+-dependent enzyme | Sulfurisphaera tokodaii |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | Sulfurisphaera tokodaii | the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks | ADP + phosphate | - |
? | |
ATP + H2O | Sulfurisphaera tokodaii DSM 16993 | the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks | ADP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sulfurisphaera tokodaii | Q974S1 | - |
- |
Sulfurisphaera tokodaii DSM 16993 | Q974S1 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Sulfurisphaera tokodaii |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks | Sulfurisphaera tokodaii | ADP + phosphate | - |
? | |
ATP + H2O | the enzyme unwinds DNA in both 3'-to-5' and 5'-to-3' directions. The enzyme exhibits structure-specific single-stranded-DNA-annealing and fork regression activities in vitro | Sulfurisphaera tokodaii | ADP + phosphate | - |
? | |
ATP + H2O | the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks | Sulfurisphaera tokodaii DSM 16993 | ADP + phosphate | - |
? | |
ATP + H2O | the enzyme unwinds DNA in both 3'-to-5' and 5'-to-3' directions. The enzyme exhibits structure-specific single-stranded-DNA-annealing and fork regression activities in vitro | Sulfurisphaera tokodaii DSM 16993 | ADP + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Hjm/Hel308A DNA helicase | - |
Sulfurisphaera tokodaii |
STK_05900 | locus name | Sulfurisphaera tokodaii |
StoHjm | - |
Sulfurisphaera tokodaii |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks | Sulfurisphaera tokodaii |