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Literature summary for 5.6.2.4 extracted from

  • Tran, N.Q.; Pham, X.H.; Tuteja, R.; Tuteja, N.
    Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin (2011), Plant Signal. Behav., 6, 327-329.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.2.4

Inhibitors

Inhibitors Comment Organism Structure
actinomycin
-
 Pisum sativum
daunorubicin less efficient inhibition of DNA helicase activity, but no inhibition of ATPase activity Pisum sativum
doxorubicin less efficient inhibition of DNA helicase activity, but no inhibition of ATPase activity Pisum sativum
Nogalamycin
-
 Pisum sativum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
93000
-
 single subunit Pisum sativum
560000
-
 homohexamer Pisum sativum

Organism

Organism UniProt Comment Textmining
Pisum sativum Q8H1A3
-
-

Subunits

Subunits Comment Organism
hexamer homohexamer, 6 * 93000 Pisum sativum

Synonyms

Synonyms Comment Organism
MCM6 DNA helicase
-
 Pisum sativum

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Pisum sativum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Pisum sativum

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.001
-
 Nogalamycin pH 8.0, 37°C, inhibition of DNA helicase activity Pisum sativum
0.01
-
 actinomycin pH 8.0, 37°C, inhibition of DNA helicase activity Pisum sativum
0.017
-
 Nogalamycin pH 8.0, 37°C, inhibition of ATPase activity Pisum sativum
0.1
-
 actinomycin pH 8.0, 37°C, inhibition of ATPase activity Pisum sativum