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Literature summary for 5.6.2.3 extracted from

  • Wolski, S.C.; Kuper, J.; Hänzelmann, P.; Truglio, J.J.; Croteau, D.L.; van Houten, B.; Kisker, C.
    Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD (2008), PLoS Biol., 6, e149.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
vapor diffusion in hanging drop method Thermoplasma acidophilum

Metals/Ions

Metals/Ions Comment Organism Structure
4Fe-4S cluster the enzyme contains a 4Fe-4S cluster Thermoplasma acidophilum

Organism

Organism UniProt Comment Textmining
Thermoplasma acidophilum Q9HM14
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O utilizes the energy from ATP hydrolysis to unwind DNA with 5' to 3' polarity Thermoplasma acidophilum ADP + phosphate
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Synonyms

Synonyms Comment Organism
XDP
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Thermoplasma acidophilum

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
21
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assay at room temperature Thermoplasma acidophilum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
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assay at Thermoplasma acidophilum