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Literature summary for 5.6.2.3 extracted from

  • Constantinesco, F.; Forterre, P.; Koonin, E.V.; Aravind, L.; Elie, C.
    A bipolar DNA helicase gene, herA, clusters with rad50, mre11 and nurA genes in thermophilic archaea (2004), Nucleic Acids Res., 32, 1439-1447.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.2.3

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Sulfolobus acidocaldarius

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Sulfolobus acidocaldarius the archaeal Rad50-Mre11 complex might act in association with a 5' to 3' exonuclease (NurA) and a bipolar DNA helicase indicating a probable involvement in the initiation step of homologous recombination ADP + phosphate
-
 ?
ATP + H2O Sulfolobus acidocaldarius DSM 639 the archaeal Rad50-Mre11 complex might act in association with a 5' to 3' exonuclease (NurA) and a bipolar DNA helicase indicating a probable involvement in the initiation step of homologous recombination ADP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Sulfolobus acidocaldarius
-
-
-
Sulfolobus acidocaldarius DSM 639
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sulfolobus acidocaldarius

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O the archaeal Rad50-Mre11 complex might act in association with a 5' to 3' exonuclease (NurA) and a bipolar DNA helicase indicating a probable involvement in the initiation step of homologous recombination Sulfolobus acidocaldarius ADP + phosphate
-
 ?
ATP + H2O the helicases is able to utilize either 3' or 5' single-stranded DNA extensions for loading and subsequent DNA duplex unwinding Sulfolobus acidocaldarius ADP + phosphate
-
 ?
ATP + H2O the archaeal Rad50-Mre11 complex might act in association with a 5' to 3' exonuclease (NurA) and a bipolar DNA helicase indicating a probable involvement in the initiation step of homologous recombination Sulfolobus acidocaldarius DSM 639 ADP + phosphate
-
 ?
ATP + H2O the helicases is able to utilize either 3' or 5' single-stranded DNA extensions for loading and subsequent DNA duplex unwinding Sulfolobus acidocaldarius DSM 639 ADP + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
HerA
-
 Sulfolobus acidocaldarius