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Literature summary for 5.6.2.3 extracted from

  • Li, Z.; Lu, S.; Hou, G.; Ma, X.; Sheng, D.; Ni, J.; Shen, Y.
    Hjm/Hel308A DNA helicase from Sulfolobus tokodaii promotes replication fork regression and interacts with Hjc endonuclease in vitro (2008), J. Bacteriol., 190, 3006-3017.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.2.3

Cloned(Commentary)

Cloned (Comment) Organism
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 Sulfurisphaera tokodaii

Inhibitors

Inhibitors Comment Organism Structure
additional information the Holliday junction-specific endonuclease from Sulfolobus tokodaii (StoHjc) inhibits in vitro Sulfurisphaera tokodaii

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ Mg2+-dependent enzyme Sulfurisphaera tokodaii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Sulfurisphaera tokodaii the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks ADP + phosphate
-
 ?
ATP + H2O Sulfurisphaera tokodaii DSM 16993 the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks ADP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Sulfurisphaera tokodaii Q974S1
-
-
Sulfurisphaera tokodaii DSM 16993 Q974S1
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sulfurisphaera tokodaii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks Sulfurisphaera tokodaii ADP + phosphate
-
 ?
ATP + H2O the enzyme unwinds DNA in both 3'-to-5' and 5'-to-3' directions. The enzyme exhibits structure-specific single-stranded-DNA-annealing and fork regression activities in vitro Sulfurisphaera tokodaii ADP + phosphate
-
 ?
ATP + H2O the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks Sulfurisphaera tokodaii DSM 16993 ADP + phosphate
-
 ?
ATP + H2O the enzyme unwinds DNA in both 3'-to-5' and 5'-to-3' directions. The enzyme exhibits structure-specific single-stranded-DNA-annealing and fork regression activities in vitro Sulfurisphaera tokodaii DSM 16993 ADP + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
Hjm/Hel308A DNA helicase
-
 Sulfurisphaera tokodaii
STK_05900 locus name Sulfurisphaera tokodaii
StoHjm
-
 Sulfurisphaera tokodaii

General Information

General Information Comment Organism
physiological function the enzyme physically interacts with StoHjc, the Holliday junction-specific endonuclease from Sulfolobus tokodaii. The unwinding activity of the helicase (StoHjm) is inhibited by StoHjc in vitro. These results may suggest that the Hjm/Hel308 family helicases, in association with Hjc endonucleases, are involved in processing of stalled replication forks Sulfurisphaera tokodaii