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Literature summary for 5.6.2.3 extracted from
- TbPIF1, a Trypanosoma brucei mitochondrial DNA helicase, is essential for kinetoplast minicircle replication (2010), J. Biol. Chem., 285, 7056-7066.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Trypanosoma brucei | Q384Y1 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TbPIF1 | - |
Trypanosoma brucei |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | RNAi of TbPIF1 causes a growth defect and kinetoplast DNA loss. Minicircle replication intermediates decrease during RNAi, and there is an accumulation of multiply interlocked, covalently closed minicircle dimers (fraction U) | Trypanosoma brucei |
| physiological function | TbPIF1 functions in minicircle replication | Trypanosoma brucei |
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Release 2023.1 (January 2023)
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