Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | low salt conditions enhance unwinding by monomeric NS3 | Hepacivirus C |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hepacivirus C | P26663 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | unwinds RNA in a discontinuous manner, pausing after long apparent steps of unwinding. It is proposed that the large kinetic step size of NS3 unwinding reflects a delayed, periodic release of the separated RNA product strand from a secondary binding site that is located in the NTPase domain (domain II) of NS3 | Hepacivirus C | ADP + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DEx(H/D)RNA helicase | - |
Hepacivirus C |