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Literature summary for 3.4.22.B80 extracted from
- Structure-based screening to discover new inhibitors for papain-like proteinase of SARS-CoV-2 an in silico study (2021), J. Proteome Res., 20, 1015-1026 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| GRL0617 | structure-based screening based on the inhibitor GRL0617 to discover new inhibitors for papain-like proteinase of SARS-CoV-2. Rediscovery of analgesic, anti-inflammatory, antibacterial, or antiviral drugs as promising pharmaceutical candidates against SARS-CoV-2 | Severe acute respiratory syndrome coronavirus 2 |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Severe acute respiratory syndrome coronavirus 2 | P0DTD1 | SARS-CoV-2 | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PLpro | - |
Severe acute respiratory syndrome coronavirus 2 |
| SARS-CoV-2 papain-like protease | - |
Severe acute respiratory syndrome coronavirus 2 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme mediates the processing of the viral replicase polyprotein | Severe acute respiratory syndrome coronavirus 2 |
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Release 2023.1 (January 2023)
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