Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.B80 extracted from

  • Huynh, T.; Cornell, W.; Luan, B.
    In silico exploration of inhibitors for SARS-CoV-2s papain-like protease (2021), Front. Chem., 8, 624163 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.B80

Inhibitors

Inhibitors Comment Organism Structure
additional information in silico high-throughput screening of all FDA-approved drugs via the flexible docking simulation for potential inhibitors of PLpro Severe acute respiratory syndrome coronavirus 2
N-[(2-methoxypyridin-4-yl)methyl]-1-[1-(naphthalen-1-yl)ethyl]piperidine-4-carboxamide i.e. rac5c, MD simulation confirms that rac5c can be bound stably inside the substrate-binding site of PLpro Severe acute respiratory syndrome coronavirus 2

Organism

Organism UniProt Comment Textmining
Severe acute respiratory syndrome coronavirus 2 P0DTD1 SARS-CoV-2
-

Synonyms

Synonyms Comment Organism
PLpro
-
 Severe acute respiratory syndrome coronavirus 2
SARS-CoV-2 papain-like protease
-
 Severe acute respiratory syndrome coronavirus 2