Literature summary for 3.4.22.B80 extracted from

Li, S.; Wang, C.; Jou, Y.; Yang, T.; Huang, S.; Wan, L.; Lin, Y.; Lin, C.
SARS coronavirus papain-like protease induces Egr-1-dependent up-regulation of TGF-beta via ROS/p38 MAPK/STAT3 pathway (2016), Sci. Rep., 6, 25754 .

Search for more literature for 3.4.22.B80

Organism

Organism	UniProt	Comment	Textmining
Severe acute respiratory syndrome-related coronavirus	-	human, i.e. SARS-CoV	-

Synonyms

Synonyms	Comment	Organism
SARS coronavirus papain-like protease	-	Severe acute respiratory syndrome-related coronavirus
SARS-CoV PLpro	-	Severe acute respiratory syndrome-related coronavirus

General Information

General Information	Comment	Organism
physiological function	the enzyme significantly triggers Egr-1 dependent activation of TGF-beta1 promoter via ROS/p38 MAPK/STAT3 pathway	Severe acute respiratory syndrome-related coronavirus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)