Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CLIK-148 | specific cathepsin L inhibitor | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
27000 | - |
mature cathepsin L, SDS-PAGE | Mus musculus |
40000 | - |
pro-cathepsin L, SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
AtT-20 cell | - |
Mus musculus | - |
brain cortex | - |
Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
CatL | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | in cathepsin L knockout mice, cholecystokinin 8 levels are substantially reduced in brain cortex by an average of 75% | Mus musculus |
physiological function | cathepsin L functions as a major protease responsible for cholecystokinin 8 production in mouse brain cortex, and participates with prohormone convertase 1/3 for cholecystokinin 8 production in pituitary cells | Mus musculus |