Inhibitors | Comment | Organism | Structure |
---|---|---|---|
E-64c | inhibition of Cathepsin B alone not only reduces hyperthermic injury-induced apoptosis significantly but enhances the beneficial effects of preinduction of HSP-70 in reducing hyperthermic injury-induced apoptosis in H9C2 cells significantly | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P00787 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
H9c2 cell | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
cathepsin B | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | cathepsin B is involved in hyperthermic injury-induced cardiomyocyte apoptosis in H9C2 cells and HSP-70 protects these cells from hyperthermic injury-induced cardiomyocyte apoptosis through cathepsin B pathways | Rattus norvegicus |