Literature summary for 3.4.21.B2 extracted from

Wang, H.; Sun, Q.; Wu, Y.; Wang, L.; Zhou, C.; Ma, W.; Zhang, Y.; Wang, S.; Zhang, S.
Granzyme M expressed by tumor cells promotes chemoresistance and EMT in vitro and metastasis in vivo associated with STAT3 activation (2015), Oncotarget, 6, 5818-5831 .

Search for more literature for 3.4.21.B2

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P51124	-	-
Mus musculus	O08643	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
4T1 cell	-	Mus musculus	-
B-16 cell	-	Mus musculus	-
colonic cancer cell line	-	Mus musculus	-
CT-26 cell	-	Mus musculus	-
Hep-G2 cell	-	Homo sapiens	-
HT-29 cell	-	Homo sapiens	-
PC-3 cell	-	Homo sapiens	-
PC-3M cell	-	Homo sapiens	-
TC-1 cell	-	Mus musculus	-

General Information

General Information	Comment	Organism
physiological function	granzyme M induces the epithelial mesenchymal transition in cancer cells associated with STAT3 activation. It increases chemoresistance, colony formation, cytokine secretion and invasiveness	Homo sapiens
physiological function	granzyme M induces the epithelial mesenchymal transition in cancer cells associated with STAT3 activation. It increases chemoresistance, colony formation, cytokine secretion and invasiveness	Mus musculus

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Release 2023.1 (January 2023)