KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
10.7 | - |
p-nitrophenyl-alpha-D-mannopyranoside | - |
Rattus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)Manbeta(1-4)GlcNAc + H2O | Rattus sp. | - |
alpha-D-mannopyranose + ? | - |
? | |
Manalpha(1-2)Manalpha(1-3)Manbeta(1-4)GlcNAc + H2O | Rattus sp. | - |
alpha-D-mannopyranose + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus sp. | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | contains mainly N-linked oligosaccharides, small amounts of fucose, galactose, glucose | Rattus sp. |
Purification (Comment) | Organism |
---|---|
to homogeneity, chromatography steps | Rattus sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epididymis | - |
Rattus sp. | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
153 | - |
- |
Rattus sp. |
Storage Stability | Organism |
---|---|
0-4°C, pH 6.0, several weeks | Rattus sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)Manbeta(1-4)GlcNAc + H2O | - |
Rattus sp. | alpha-D-mannopyranose + ? | - |
? | |
Manalpha(1-2)Manalpha(1-3)Manbeta(1-4)GlcNAc + H2O | - |
Rattus sp. | alpha-D-mannopyranose + ? | - |
? | |
p-nitrophenyl-alpha-D-mannopyranoside + H2O | - |
Rattus sp. | p-nitrophenol + alpha-D-mannopyranose | - |
? |
Subunits | Comment | Organism |
---|---|---|
oligomer | composed of 60 and 31 kDa subunits | Rattus sp. |
Synonyms | Comment | Organism |
---|---|---|
lysosomal alpha-D-mannosidase | - |
Rattus sp. |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4.4 | 4.6 | - |
Rattus sp. |