Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-isobutyl-1-methylxanthine | - |
Plasmodium falciparum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gametocyte | - |
Plasmodium falciparum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3',5'-cGMP + H2O | - |
Plasmodium falciparum | 5'-GMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cGMP-PDE | - |
Plasmodium falciparum |
PDE | - |
Plasmodium falciparum |
phosphodiesterase | - |
Plasmodium falciparum |
General Information | Comment | Organism |
---|---|---|
malfunction | disruption of the cyclic nucleotide phosphodiesterase PDEdelta gene causes significantly reduced cGMP-PDE activity and greatly reduced ability to undergo gametogenesis | Plasmodium falciparum |
physiological function | PDEdelta plays a crucial role in regulating cGMP levels during sexual development | Plasmodium falciparum |