Application | Comment | Organism |
---|---|---|
medicine | dietary manipulation using ketone bodies in accordance with SCOT expression may be a novel therapeutic strategy for neuroblastoma | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + acetoacetate | Homo sapiens | - |
succinate + acetoacetyl-CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
fibroblast | from foreskin | Homo sapiens | - |
HFF-1 cell | - |
Homo sapiens | - |
neuroblastoma cell | decreased expression of SCOT protein, neuroblastoma cells are unable to use ketone bodies as an energy source | Homo sapiens | - |
SK-N-AS cell | decreased expression of SCOT protein, neuroblastoma cells are unable to use ketone bodies as an energy source | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + acetoacetate | - |
Homo sapiens | succinate + acetoacetyl-CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCOT | - |
Homo sapiens |
succinyl-coenzyme A:3-oxoacid coenzyme A transferase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
succinyl-CoA | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | SCOT is a key enzyme involved in ketone body metabolism | Homo sapiens |