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Literature summary for 2.7.11.8 extracted from

  • Zhi, F.; Zhou, G.; Shao, N.; Xia, X.; Shi, Y.; Wang, Q.; Zhang, Y.; Wang, R.; Xue, L.; Wang, S.; Wu, S.; Peng, Y.; Yang, Y.
    miR-106a-5p inhibits the proliferation and migration of astrocytoma cells and promotes apoptosis by targeting FASTK (2013), PLoS ONE, 8, e72390.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.8

Application

Application Comment Organism
medicine the increased enzyme expression of is significantly associated with poor survival outcome in astrocytoma patients Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [Fas-activated serine/threonine protein] Homo sapiens
-
 ADP + [Fas-activated serine/threonine phosphoprotein]
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocytoma cell
-
 Homo sapiens
-
U-251 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [Fas-activated serine/threonine protein]
-
 Homo sapiens ADP + [Fas-activated serine/threonine phosphoprotein]
-
 ?

Synonyms

Synonyms Comment Organism
FASTK
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens miR-106a-5p upregulates enzyme expression via a post-transcriptional mechanism and by affecting its mRNA stability up