General Stability | Organism |
---|---|
oxidation of PKA subunits occurs in intact cardiac myocytes | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P27791 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cardiac muscle fiber | - |
Rattus norvegicus | - |
Subunits | Comment | Organism |
---|---|---|
heterotetramer | PKA is a heterotetrameric kinase comprising two regulatory and two catalytic subunits. Binding of two molecules of cAMP to each of the two regulatory subunits (PKA-R) induces the release of the active catalytic subunits (PKA-C) | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
PKA-C | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
metabolism | the contraction and relaxation of the heart is controlled by stimulation of the b1-adrenoreceptor (AR) signaling cascade, which leads to activation of cAMP-dependent protein kinase (PKA) and subsequent cardiac protein phosphorylation | Rattus norvegicus |