Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-([(1-benzyl-2-hydroxyethyl)imino]methyl)-4Hchromen-4-one | - |
Escherichia coli | |
3-([(2, 4-dichlorophenyl)imino]methyl)-4H-chromen-4-one | - |
Escherichia coli | |
3-([(2-([-(4-oxo-4H-chromen-3-yl)methylidene]amino)ethyl)imino] methyl)-4H-chromen-4-one | - |
Escherichia coli | |
3-([(2-benzoyl-4-chlorophenyl)imino]methyl)-4Hchromen-4-one | - |
Escherichia coli | |
3-([(2-methyl-6-nitrophenyl)imino]methyl)-4Hchromen-4-one | - |
Escherichia coli | |
3-([(3-hydroxy-2-pyridinyl)imino]methyl)-4H-chromen-4-one | - |
Escherichia coli | |
3-([(3-methoxy-4-methylphenyl)imino]methyl)-4Hchromen-4-one | - |
Escherichia coli | |
3-([(3-methylphenyl)imino]methyl)-4H-chromen-4-one | - |
Escherichia coli | |
7-deazaxanthine | - |
Escherichia coli | |
additional information | Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors, no inhibition by 3-formylchromone and 3-methyl-7-hydroxychromone, and by derivatives 3-[(4-pyridinylimino) methyl]-4H-chromen-4-one, 3-[(3-pyridinylimino) methyl]-4H-chromen-4-one, 3-([(3-methoxyphenyl)imino]methyl)-4H-chromen-4-one, 3-([(2-methoxy-4-nitrophenyl) imino] methyl)-4Hchromen-4-one, 2-([-(4-oxo-4H-chromen-3-yl) methylidene]amino)benzoic acid, 3-([(4-methylphenyl)imino]methyl)-4H-chromen-4-one, 3-([(2,6-dimethylphenyl)imino]methyl)-4H-chromen-4-one, and 3-[bis(tert-butylamino)methyl]-4H-chromen-4-one, overview | Escherichia coli | |
N'-[-(4-oxo-4H-chromen-3-yl)methylidene]propanohydrazide | - |
Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Escherichia coli | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.02 | - |
pH 7.6 | Escherichia coli | 3-([(3-methoxy-4-methylphenyl)imino]methyl)-4Hchromen-4-one | |
0.0393 | - |
- |
Escherichia coli | 7-deazaxanthine | |
0.04 | - |
pH 7.6 | Escherichia coli | 3-([(2, 4-dichlorophenyl)imino]methyl)-4H-chromen-4-one | |
0.067 | - |
pH 7.6 | Escherichia coli | 3-([(3-methylphenyl)imino]methyl)-4H-chromen-4-one | |
0.076 | - |
pH 7.6 | Escherichia coli | 3-([(2-benzoyl-4-chlorophenyl)imino]methyl)-4Hchromen-4-one | |
0.146 | - |
pH 7.6 | Escherichia coli | N'-[-(4-oxo-4H-chromen-3-yl)methylidene]propanohydrazide | |
0.15 | - |
pH 7.6 | Escherichia coli | 3-([(2-([-(4-oxo-4H-chromen-3-yl)methylidene]amino)ethyl)imino] methyl)-4H-chromen-4-one | |
0.34 | - |
pH 7.6 | Escherichia coli | 3-([(3-hydroxy-2-pyridinyl)imino]methyl)-4H-chromen-4-one | |
0.473 | - |
pH 7.6 | Escherichia coli | 3-([(1-benzyl-2-hydroxyethyl)imino]methyl)-4Hchromen-4-one | |
0.48 | - |
pH 7.6 | Escherichia coli | 3-([(2-methyl-6-nitrophenyl)imino]methyl)-4Hchromen-4-one |