Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(2-hydroxyethoxymethyl)thymine | - |
Escherichia coli | |
2,2'-O-anhydrouridine | - |
Escherichia coli | |
5-fluoro-1-(tetrahydrofur-2-yl)uracil | - |
Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.25 | - |
4-thiothymidine | pH 7.5, 25°C | Escherichia coli | |
0.3 | - |
thymidine | pH 7.5, 25°C | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-thiothymidine + phosphate | - |
Escherichia coli | 4-thiothymine + 2-deoxy-D-ribose 1-phosphate | - |
? | |
thymidine + phosphate | - |
Escherichia coli | thymine + 2-deoxy-D-ribose 1-phosphate | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
63 | - |
4-thiothymidine | pH 7.5, 25°C | Escherichia coli | |
198 | - |
thymidine | pH 7.5, 25°C | Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.4 | - |
2,2'-O-anhydrouridine | pH 7.5, 25°C, activity with 4-thiothymidine | Escherichia coli | |
0.4 | - |
5-fluoro-1-(tetrahydrofur-2-yl)uracil | pH 7.5, 25°C, activity with thymidine | Escherichia coli | |
0.45 | - |
5-fluoro-1-(tetrahydrofur-2-yl)uracil | pH 7.5, 25°C, activity with 4-thiothymidine | Escherichia coli | |
0.5 | - |
2,2'-O-anhydrouridine | pH 7.5, 25°C, activity with thymidine | Escherichia coli | |
1.5 | - |
1-(2-hydroxyethoxymethyl)thymine | pH 7.5, 25°C, activity with 4-thiothymidine | Escherichia coli |