Organism | UniProt | Comment | Textmining |
---|---|---|---|
Listeria monocytogenes | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
lmo1080 | - |
Listeria monocytogenes |
RmlT | - |
Listeria monocytogenes |
General Information | Comment | Organism |
---|---|---|
physiological function | gene RmlT is part of the rmlABCD locus encoding the biosynthetic pathway for L-rhamnose. Transferase RmlT is required for the incorporation of L-rhamnose into wall teichoic acids. Wall teichoic acids isolated from bacteria lacking RmlT display a faster migration in gel and do not contain any trace of L-rhamnose. The presence of L-rhamnosylated wall teichoic acids at the surface of Listeria monocytogenes delays the crossing of the cell wall by antimicrobial peptides and postpones their contact with the listerial membrane. Wall teichoic acids L-rhamnosylation promotes Listeri monocytogenes survival by decreasing the cell wall permeability to antimicrobial peptides, thus hindering their access and detrimental interaction with the plasma membrane | Listeria monocytogenes |