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Literature summary for 2.4.1.255 extracted from

  • Seo, H.G.; Kim, H.B.; Kang, M.J.; Ryum, J.H.; Yi, E.C.; Cho, J.W.
    Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation (2016), Sci. Rep., 6, 34614 .
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol the enzyme exists in the nucleus and cytosol simultaneously Homo sapiens 5829
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nucleus amino acids residues 451-453 (DFP) are characterised as the nuclear localisation signal of the enzyme. Tne enzyme binds the importin alpha5 protein, and this association is abolished when the DFP motif of the enzyme is mutated or deleted. O-GlcNAcylation of Ser389, which resides in the tetratricopeptide repeats, plays an important role in the nuclear localisation of the enzyme Homo sapiens 5634
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Organism

Organism UniProt Comment Textmining
Homo sapiens O15294
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Synonyms

Synonyms Comment Organism
O-GlcNAc transferase
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 Homo sapiens
OGT
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 Homo sapiens