Literature summary for 2.4.1.255 extracted from

Sacoman, J.L.; Dagda, R.Y.; Burnham-Marusich, A.R.; Dagda, R.K.; Berninsone, P.M.
Mitochondrial O-GlcNAc transferase (mOGT) regulates mitochondrial structure, function, and survival in HeLa cells (2017), J. Biol. Chem., 292, 4499-4518 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Homo sapiens	5739	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O15294	O-linked N-acetylglucosamine transferase is encoded by a single gene that yields nucleocytosolic and mitochondrial isoforms	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HeLa cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
mOGT	-	Homo sapiens
O-GlcNAc transferase	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	reducing endogenous mOGT expression leads to alterations in mitochondrial structure and function, including Drp1-dependent mitochondrial fragmentation, reduction in mitochondrial membrane potential, and a significant loss of mitochondrial content in the absence of mitochondrial ROS	Homo sapiens
physiological function	mitochondrial O-GlcNAc transferase regulates mitochondrial structure, function, and survival in HeLa cell	Homo sapiens

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Release 2023.1 (January 2023)