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Literature summary for 2.4.1.15 extracted from

  • Chen, J.X.; Lyu, Z.H.; Wang, C.Y.; Cheng, J.; Lin, T.
    RNA interference of a trehalose-6-phosphate synthase gene reveals its roles in the biosynthesis of chitin and lipids in Heortia vitessoides (Lepidoptera Crambidae) (2020), Insect Sci., 27, 212-223 .
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-glucose + D-glucose 6-phosphate Heortia vitessoides
-
 UDP + alpha,alpha-trehalose 6-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Heortia vitessoides
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fat body high expression Heortia vitessoides
-
larva
-
 Heortia vitessoides
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + D-glucose 6-phosphate
-
 Heortia vitessoides UDP + alpha,alpha-trehalose 6-phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 93480, calculated from amino acid sequence Heortia vitessoides

Synonyms

Synonyms Comment Organism
TPS
-
 Heortia vitessoides
trehalose-6-phosphate synthase
-
 Heortia vitessoides

pI Value

Organism Comment pI Value Maximum pI Value
Heortia vitessoides calculated from amino acid sequence
-
 7.1

Expression

Organism Comment Expression
Heortia vitessoides the enzyme is highly expressed after pupation or before molting up

General Information

General Information Comment Organism
malfunction enzyme knockdown results in optimal interference at 24 h and 36 h postinjection and causes a sharp decline in the survival rate during the 5th instar larval-pupal stage and obviously abnormal or lethal phenotypes. Silencing of the enzyme inhibits chitin biosynthesis. Furthermore, the expression levels of two genes associated with lipid biosynthesis are upregulated Heortia vitessoides
physiological function the enzyme is essential for the normal growth and development of Heortia vitessoides Heortia vitessoides