Application | Comment | Organism |
---|---|---|
medicine | the majority of N-glycans of a recombinant antibody produced in Nicotiana tabacum expressing GnT-III is bisected and devoid of paucimannosidic structures. This might improve the efficacy of therapeutic antibodies produced in the transgenic plants | Homo sapiens |
synthesis | introduction of human N-acetylglucosaminyltransferase gene into tobacco plants leads to highly efficient synthesis of bisected N-glycans. The majority of N-glycans of an antibody produced in a plant expressing GnT-III is also bisected. This might improve the efficacy of therapeutic antibodies produced in this type of transgenic plant | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
introduction of human N-acetylglucosaminyltransferase (GnT)-III gene into Nicotiana tabacum leads to highly efficient synthesis of bisected N-glycans | Homo sapiens |
introduction of human N-acetylglucosaminyltransferase gene into tobacco plants leads to highly efficient synthesis of bisected N-glycans. The majority of N-glycans of an antibody produced in a plant expressing GnT-III is also bisected. This might improve the efficacy of therapeutic antibodies produced in this type of transgenic plant | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
(GnT)-III | - |
Homo sapiens |
N-acetylglucosaminyltransferase III | - |
Homo sapiens |