Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mesocricetus auratus | in brain cells with down-regulated enzyme activity, normal prion proteins PrPC get conversed to pathogenic prion protein PrPSc due to a lower amount of glycans with bisecting N-acetylglucosamine residues | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mesocricetus auratus | - |
forming normal prion protein PrPC and pathogenic prion protein PrPSc | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | cells forming normal prion protein PrPC with normal enzyme activity, and pathogenic prion protein PrPSc with reduced enzyme activity | Mesocricetus auratus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | in brain cells with down-regulated enzyme activity, normal prion proteins PrPC get conversed to pathogenic prion protein PrPSc due to a lower amount of glycans with bisecting N-acetylglucosamine residues | Mesocricetus auratus | ? | - |
? | |
UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R | - |
Mesocricetus auratus | UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-(N-acetyl-beta-D-glucosaminyl-1,4)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R | incorporates a N-acetylglucosamine residue in beta-1,4-linkage to beta-linked mannosyl, i.e. bisecting N-acetylglucosamine | ? |
Synonyms | Comment | Organism |
---|---|---|
GnTIII | - |
Mesocricetus auratus |