Activating Compound | Comment | Organism | Structure |
---|---|---|---|
AMP | - |
Carassius carassius | |
additional information | anoxia (or ischemia) results in the rapid activation of glycogen phosphorylase | Carassius carassius |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[(1->4)-alpha-D-glucosyl]n + phosphate | Carassius carassius | - |
[(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Carassius carassius | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | the glycogen phosphorylase dimer can exist in either in unphosphorylated glycogen phosphorylase b or phosphorylated glycogen phosphorylase a form depending on hormonal activation of kinase/phosphatase reactions | Carassius carassius |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Carassius carassius | - |
heart | - |
Carassius carassius | - |
liver | - |
Carassius carassius | - |
additional information | when seasonal temperature changes are taken into account, the activity of GP during the anoxic midwinter is only 4-6% of its summer time activity in the muscle, heart and liver, and 13% in brain | Carassius carassius | - |
muscle | - |
Carassius carassius | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[(1->4)-alpha-D-glucosyl]n + phosphate | - |
Carassius carassius | [(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
glycogen phosphorylase | - |
Carassius carassius |
GPA | - |
Carassius carassius |
GPb | - |
Carassius carassius |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
- |
Carassius carassius |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
5 | 35 | in the tissues, except the gill, the basal and total activities of glycogen phosphorylase increase from 5 to 25°C, but less steeply between 5 and 15°C than between 15 and 25°C, inactivation starts above 25°C | Carassius carassius |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.1 | - |
assay at | Carassius carassius |
General Information | Comment | Organism |
---|---|---|
additional information | the glycogen phosphorylase dimer can exist in either in unphosphorylated glycogen phosphorylase b or phosphorylated glycogen phosphorylase a form depending on hormonal activation of kinase/phosphatase reactions | Carassius carassius |
physiological function | glycogen phosphorylase is a rate-limiting enzyme of glycogen degradation | Carassius carassius |