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Literature summary for 2.3.1.B45 extracted from

  • Linde, M.; Peterhoff, D.; Sterner, R.; Babinger, P.
    Identification and characterization of heptaprenylglyceryl phosphate processing enzymes in Bacillus subtilis (2016), J. Biol. Chem., 291, 14861-14870 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.B45

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.039
-
 geranylgeranylglycerol pH 7.5, 40°C Bacillus subtilis
0.538
-
 acetyl-CoA pH 7.5, 40°C Bacillus subtilis

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane not an integral membrane protein Bacillus subtilis 16020
-

Organism

Organism UniProt Comment Textmining
Bacillus subtilis
-
-
-
Bacillus subtilis 168
-
-
-

Reaction

Reaction Comment Organism Reaction ID
acetyl-CoA + heptaprenylglycerol = CoA + O-acetylheptaprenylglycerol (1) Bacillus subtilis
a
acetyl-CoA + O-acetylheptaprenylglycerol = CoA + O-1,2-diacetylheptaprenylglycerol (2) Bacillus subtilis
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + geranylgeranylglycerol
-
 Bacillus subtilis CoA + O-acetylgeranylgeranylglycerol
-
 ?
acetyl-CoA + geranylgeranylglycerol
-
 Bacillus subtilis 168 CoA + O-acetylgeranylgeranylglycerol
-
 ?
acetyl-CoA + heptaprenylglycerol
-
 Bacillus subtilis CoA + O-acetylheptaprenylglycerol
-
 ?
acetyl-CoA + heptaprenylglycerol
-
 Bacillus subtilis 168 CoA + O-acetylheptaprenylglycerol
-
 ?
acetyl-CoA + O-acetylgeranylgeranylglycerol
-
 Bacillus subtilis CoA + O-1,2-diacetylgeranylgeranylglycerol
-
 ?
acetyl-CoA + O-acetylgeranylgeranylglycerol
-
 Bacillus subtilis 168 CoA + O-1,2-diacetylgeranylgeranylglycerol
-
 ?
acetyl-CoA + O-acetylheptaprenylglycerol
-
 Bacillus subtilis CoA + O-1,2-diacetylheptaprenylglycerol
-
 ?
acetyl-CoA + O-acetylheptaprenylglycerol
-
 Bacillus subtilis 168 CoA + O-1,2-diacetylheptaprenylglycerol
-
 ?

Synonyms

Synonyms Comment Organism
YvoF
-
 Bacillus subtilis

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.48
-
 geranylgeranylglycerol pH 7.5, 40°C Bacillus subtilis
0.67
-
 acetyl-CoA pH 7.5, 40°C Bacillus subtilis

General Information

General Information Comment Organism
physiological function In Bacillales, heptaprenylglyceryl phosphate is dephosphorylated and acetylated to become a part of the cellular membrane. YvoF is the acetyltransferase responsible for two subsequent acetylation steps of heptaprenylglycerol. Knockout strains lacking YvoF activity lack single acetylated O-acetylheptaprenylglycerol and double acetylated O-1,2-diacetylheptaprenylglycerol Bacillus subtilis

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
1.25
-
 geranylgeranylglycerol pH 7.5, 40°C Bacillus subtilis
1.3
-
 acetyl-CoA pH 7.5, 40°C Bacillus subtilis